Stroke is the second leading cause of death and major cause of long-term disability, directly impacting the quality of life, worldwide. Strokes with more rare, and unknown causes unfortunately receive little to no attention due to the heterogeneity of disorders and a poor understanding of clinical features. There are considerable variations in the etiology of this rare sub-category of stroke; requiring heightened clinical awareness for recognition, evaluation and treatment. This book provides up-to-date guidance, through case reports concisely summarised by global leaders in the field describing the diagnosis and treatment of rare causes of stroke, from vasculitis, hypercoagulable states, hereditary and genetic factors, cardioembolism, vasculopathies, venous occlusive conditions to bone disorders. Offering practical advice and algorithms, this book aids the clinician in establishing an accurate diagnosis through detailed evaluation of such patients, leading to an early diagnosis improving risk assessment and family counselling.